Neuroimaging in Autism Spectrum Disorder
Neuroimaging has uncovered connectivity abnormalities in the brains of individuals with autism spectrum disorders (ASD). The precise connectivity abnormalities and the relationship between these abnormalities and cognition/ASD symptoms is unknown. Functional magnetic resonance imaging and other advances in neuroimaging may have clinical utility as non-invasive ways to investigate these neurochemical alterations in ASD. MRI provides dynamic insight into the functional organization of the brains’ activity and measures the function of neurotransmitter-driven networks. New applications of neuroimaging can help us evaluate treatments for patients with ASD and other neurodevelopmental disorders.
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Published Articles
Results are displayed in descending order beginning with most recent publications.
Receptive language organization in high-functioning autism
Frye RE, Beauchamp MS. Receptive language organization in high-functioning autism. J Child Neurol. 2009 Feb;24(2):231-6. doi: 10.1177/0883073808329572. PMID: 19182164; PMCID: PMC2896833.
Splenium microstructure is related to two dimensions of reading skill
Frye RE, Hasan K, Xue L, Strickland D, Malmberg B, Liederman J, Papanicolaou A. Splenium microstructure is related to two dimensions of reading skill. Neuroreport. 2008 Oct 29;19(16):1627-31. doi: 10.1097/WNR.0b013e328314b8ee. PMID: 18806688; PMCID: PMC2667961.
Touch, sound and vision in human superior temporal sulcus
Beauchamp MS, Yasar NE, Frye RE, Ro T. Touch, sound and vision in human superior temporal sulcus. Neuroimage. 2008 Jul 1;41(3):1011-20. doi: 10.1016/j.neuroimage.2008.03.015. Epub 2008 Mar 20. PMID: 18440831; PMCID: PMC2409200.
Objective Phonological and Subjective Perceptual Characteristics of Syllables Modulate Spatiotemporal Patterns of Superior Temporal Gyrus Activity
Frye RE, Fisher JM, Witzel T, Ahlfors SP, Swank P, Liederman J, Halgren E. Objective phonological and subjective perceptual characteristics of syllables modulate spatiotemporal patterns of superior temporal gyrus activity. Neuroimage. 2008 May 1;40(4):1888-901. doi: 10.1016/j.neuroimage.2008.01.048. Epub 2008 Feb 14. PMID: 18356082; PMCID: PMC2443388.
Linear coding of voice onset time
Frye RE, Fisher JM, Coty A, Zarella M, Liederman J, Halgren E. Linear coding of voice onset time. J Cogn Neurosci. 2007 Sep;19(9):1476-87. doi: 10.1162/jocn.2007.19.9.1476. PMID: 17714009; PMCID: PMC2393546.
Choroid plexus papilloma expansion over 7 years in Aicardi syndrome
Frye RE, Polling JS, Ma LC. Choroid plexus papilloma expansion over 7 years in Aicardi syndrome. J Child Neurol. 2007 Apr;22(4):484-7. doi: 10.1177/0883073807302759. PMID: 17621535; PMCID: PMC2536525.
Other Resources