Seizures and Epilepsy in Autism Spectrum Disorder
Seizures are very common in individuals with autism as are abnormal electroencephalogram recordings with seizure-like activity. Additionally a diagnosis of epilepsy is found in up to 40% of children with autism and, in many cases, is refractory to treatment. The pathology that causes epilepsy also has been implemented in children with autism.
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Published Articles
Results are displayed in descending order beginning with most recent publications.
Synchrony 2022: Epilepsy and Seizures in Autism Spectrum Disorder Roundtable
Frye, R.E.; Nanda, H.; Pleasure, S.J.; Casanova, M.F.; Boles, R.G.; Lewine, J.; Gaitanis, J.; Adams, J.B. Synchrony 2022: Epilepsy and Seizures in Autism Spectrum Disorder Roundtable. J. Pers. Med. 2023, 13, 557. https://doi.org/10.3390/jpm13030557
Central Nervous System Metabolism in Autism, Epilepsy and Developmental Delays: A Cerebrospinal Fluid Analysis
Brister D, Werner BA, Gideon G, McCarty PJ, Lane A, Burrows BT, McLees S, Adelson PD, Arango JI, Marsh W, Flores A, Pankratz MT, Ly NH, Flood M, Brown D, Carpentieri D, Jin Y, Gu H, Frye RE. Central Nervous System Metabolism in Autism, Epilepsy and Developmental Delays: A Cerebrospinal Fluid Analysis. Metabolites. 2022 Apr 20;12(5):371. doi: 10.3390/metabo12050371. PMID: 35629876; PMCID: PMC9148155.
Seizures in Fragile X Syndrome: Associations and Longitudinal Analysis of a Large Clinic-Based Cohort
Berry-Kravis E, Filipink RA, Frye RE, Golla S, Morris SM, Andrews H, Choo TH, Kaufmann WE; FORWARD Consortium. Front Pediatr. 2021 Dec 30;9:736255. doi: 10.3389/fped.2021.736255. PMID: 35036394; PMCID: PMC8756611.
Rating of the Effectiveness of 26 Psychiatric and Seizure Medications for Autism Spectrum Disorder: Results of a National Survey
Coleman DM, Adams JB, Anderson AL, Frye RE. J Child Adolesc Psychopharmacol. 2019 Mar;29(2):107-123. doi: 10.1089/cap.2018.0121. Epub 2019 Feb 6. PMID: 30724573; PMCID: PMC6442266.
Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder
Frye RE, Casanova MF, Fatemi SH, Folsom TD, Reutiman TJ, Brown GL, Edelson SM, Slattery JC, Adams JB. Front Neurosci. 2016 May 10;10:192. doi: 10.3389/fnins.2016.00192. PMID: 27242398; PMCID: PMC4861974.
Metabolic and mitochondrial disorders associated with epilepsy in children with autism spectrum disorder.
Frye RE. Epilepsy Behav. 2015; 47:147-57.
A review of traditional and novel treatments for seizures in autism spectrum disorder: findings from a systematic review and expert panel
Frye RE, Rossignol D, Casanova MF, Brown GL, Martin V, Edelson S, Coben R, Lewine J, Slattery JC, Lau C, Hardy P, Fatemi SH, Folsom TD, Macfabe D, Adams JB. Front Public Health. 2013 Sep 13;1:31. doi: 10.3389/fpubh.2013.00031. PMID: 24350200; PMCID: PMC3859980.
Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey
Frye RE, Sreenivasula S, Adams JB. BMC Pediatr. 2011 May 18;11:37. doi: 10.1186/1471-2431-11-37. PMID: 21592359; PMCID: PMC3123184.
Electroencephalogram discharges in atypical cognitive development
Frye RE, Butler I, Strickland D, Castillo E, Papanicolaou A. J Child Neurol. 2010 May;25(5):556-66. doi: 10.1177/0883073809344743. Epub 2010 Mar 18. PMID: 20299700; PMCID: PMC2896832.
Other Resources
SEIZURES IN ASD
from Autism File
SEIZURES AND ASD
from The Journal of Autismone
Autism & Seizures
Title: Autism & Seizures
Date: June 16, 2020
Location: The Autism Hope Alliance
Presented by: Dr. Richard Frye, MD PhD
Seizures and Epilepsy in Autism Spectrum Disorder
Title: Seizures and Epilepsy in Autism Spectrum Disorder
Date: January 21, 2020
Location: Synchrony 2019: The BRAIN Foundation
Presented by: Dr. Richard Frye, MD PhD
