Jyonouchi, H.; Geng, L.; Rossignol, D.A.; Frye, R.E. Long COVID Syndrome Presenting as Neuropsychiatric Exacerbations in Autism Spectrum Disorder: Insights for Treatment. J. Pers. Med. 2022, 12, 1815. https://doi.org/10.3390/jpm12111815
Shimasaki C, Frye RE, Trifiletti R, Cooperstock M, Kaplan G, Melamed I, Greenberg R, Katz A, Fier E, Kem D, Traver D, Dempsey T, Latimer ME, Cross A, Dunn JP, Bentley R, Alvarez K, Reim S, Appleman J. Evaluation of the Cunningham Panel™ in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS): Changes in antineuronal antibody titers parallel changes in patient symptoms. J Neuroimmunol. 2020 Feb 15;339:577138. doi: 10.1016/j.jneuroim.2019.577138. Epub 2019 Dec 15. PMID: 31884258.
Title: Childhood Onset Neurobehavioral Syndromes: The Overlap Between Immunologic and Metabolic Etiologies
Date: August 8, 2019
Location: Lighthouse Complex Care Ltd., Neuroimmune Day
Presented by: Dr. Richard Frye, MD PhD
Frye RE, Shimasaki C. Reliability of the Cunningham Panel. Translational Psychiatry. 2019 Apr;9(1):129. DOI: 10.1038/s41398-019-0462-1. PMID: 30962420; PMCID: PMC6453973.
By Susanne Brunner
Posted: July 26, 2017
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Title: Dr. Frye Discusses Autism Spectrum Disorders, PANDAS and PANS
Date: July 1, 2016
Location: Moleculera Labs
Presented by: Dr. Richard Frye, MD PhD
Frye, R.E. N A J Med Sci. 2015;8(2):92-95
This test measures the levels of four proteins called autoantibodies and the activity of one enzyme protein. The four autoantibodies are believed to attach to nerve cells in the brain and cause them to function abnormally while the activity of the enzyme known as CamKinase II is believe to interfere with the function of nerve cells if its activity is too high. These measurements are complicated to interpret so you should discuss them with you doctor.
